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However, the expression of GPx1 has been reported to be down-regulated in thyroid cancer [44], colorectal cancer [45, 46], and gastric cancer [47], whereas GPx1 has been demonstrated to play an oncogenic role in kidney cancer [48], pancreatic cancer [49], and laryngeal squamous cell carcinoma [50]

The free radical damage to the skin is caused by the skins exposure to the suns UV rays and pollution

Against this background, our patient had malignancy, prior ICI exposure, severe postoperative pneumonia, and concomitant use of several drugs with potential hepatic and/or cutaneous toxicityconstituting a typical susceptible host plus high-risk drug exposure profile and placing him at dual high risk for both DILI and SJS/TEN

Papaya enzymes gently exfoliate the skin, removing dead cells and revealing a fresh, clean layer underneath

M., Moreau, R., Suh, J